Show HN: CUDA, Shmuda: Fold Proteins on a MacBook https://bit.ly/4oUV0Mc

Show HN: CUDA, Shmuda: Fold Proteins on a MacBook Alphafold3 used to be fodder for HPC clusters; now I've got a port running smoothly on Apple Silicon. If you have an M-series Mac (~2023-present), you can generate protein structures from sequences in minutes. Give it a try! GitHub repo: https://bit.ly/4r57KRU https://bit.ly/3LJvxqv November 17, 2025 at 01:08AM