Show HN: Constexpr.js https://bit.ly/3urbD6o

Show HN: Constexpr.js https://bit.ly/2ZFSI9R February 23, 2021 at 03:24AM

Show HN: Community of professionals, with satisfaction and transparency at core https://bit.ly/3dExT7c

Show HN: Community of professionals, with satisfaction and transparency at core https://bit.ly/3kc6jPR February 23, 2021 at 02:58AM

Show HN: Recursive – A puzzle game about recursion, patterns, and programming https://bit.ly/3qJ0mfy

Show HN: Recursive – A puzzle game about recursion, patterns, and programming https://apple.co/3aGS3eM February 22, 2021 at 08:51PM

Show HN: Note, my simple command line note taking app https://bit.ly/2MeoI1L

Show HN: Note, my simple command line note taking app https://bit.ly/3uxQjfQ February 22, 2021 at 07:19PM

Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops https://bit.ly/3aIN5OI

Launch HN: Wyndly (YC W21) – Allergy relief through at-home oral drops Hi HN, I’m Aakash, and I’m a long time HN reader. My cousin Manan and I are excited to share our startup Wyndly ( https://bit.ly/3aEMltQ ) with HN today. Wyndly is focused on making long-term allergy relief convenient through at-home allergy immunotherapy drops and telemedicine. These personalized oral drops train your immune systems to stop reacting to allergy triggers like pollen, pets, or dust. Manan is an ear-nose-and-throat surgeon and allergy doctor, and in his physical practice, he’s treated thousands of patients with at-home allergy drops, a form of allergy immunotherapy. During allergy immunotherapy, you gradually introduce your immune system to your allergy triggers. Over time, your immune system learns to tolerate these allergy triggers and stops reacting to them. For patients, this means greatly reduced allergy symptoms and long-term relief [1] without any other medicine for years after patients finish their immunotherapy. While allergy drops are 80% of allergy immunotherapy in some European countries, in the United States, allergy drops are just 5.9% of allergy immunotherapy prescriptions [2] and are really only available in university hospitals like Johns Hopkins, University of Pittsburgh, and West Virginia University [3] [4] [5]. Part of the reason for their limited availability is physician training, and another part is the health insurance system’s incentives. Most allergy doctors were trained on allergy shots, and prescribe what they are most experienced with. Additionally, health insurance programs incentivize prescribing allergy shots. In his medical training, Manan trained on both allergy drops and shots. When Manan gave his patients the choice between at-home allergy drops and allergy shots, his patients always chose drops, which are safer, convenient, and don’t require needles [6]. When Covid-19 hit Denver in March 2020, Manan switched all of his allergy drop patients to online care to continue treatment. After shelter-in-place was lifted, his patients continued online care due to the convenience, which told us one thing—patients preferred and were comfortable with telemedicine for allergy care. And that's why we started Wyndly. We’re trying to make allergy immunotherapy convenient and affordable, so that any one of the 60 million people in America suffering from allergies has the opportunity to get lifelong relief—just like braces straighten your teeth and Lasik fixes your vision. We’ve done our best to make our patient experience as easy as possible. First, we learn more about you and your allergy history. Then, our medical team creates a personalized treatment plan with treatment sent straight to your door. Most patients notice benefits at 6 months, and some patients have reported allergy symptom relief as early as 6 weeks [7]. Patients lock-in lifelong allergy relief after a few years [1]. Throughout this time, we stay in touch with the patient to work with them towards allergy relief. Please let us know if you have more questions or feedback. We love talking about the science behind allergy immunotherapy, our treatment model, and what we’re doing. We're happy to answer any questions! [1] Long-lasting effects of sublingual immunotherapy according to its duration: a 15-year prospective study https://bit.ly/37AR6mo [2] Comparison of allergen immunotherapy practice patterns in the United States and Europe https://bit.ly/3aNssB3 [3] Sublingual Immunotherapy (SLIT) for Allergy Treatment: Johns Hopkins | Q&A https://www.youtube.com/watch?v=dpWomI4iPLY [4] Benefits of Sublingual Immunotherapy | UPMC https://www.youtube.com/watch?v=TpP41WQ6pBc [5] Sublingual Immunotherapy: An Alternative to Allergy Shots https://www.youtube.com/watch?v=THszgnYNM1I [6] Efficacy and Safety of Subcutaneous and Sublingual Immunotherapy for Allergic Rhinoconjunctivitis and Asthma https://bit.ly/3sfpwms [7] Clinical improvement after escalation for sublingual immunotherapy (SLIT) https://bit.ly/37CExXM February 22, 2021 at 07:00PM

Show HN: Call a Dev – Pay Stack Overflow users $1/min for live programming help https://bit.ly/3dFysgO

Show HN: Call a Dev – Pay Stack Overflow users $1/min for live programming help https://bit.ly/3dCLqfa February 22, 2021 at 05:59PM

Show HN: Summarizing product reviews into simple bullet-point lists with GPT-3 https://bit.ly/3dz3LKg

Show HN: Summarizing product reviews into simple bullet-point lists with GPT-3 https://bit.ly/3uov6EL February 22, 2021 at 03:17PM

Show HN: Scroll – A New Way to Publish https://bit.ly/3aIBFKP

Show HN: Scroll – A New Way to Publish https://bit.ly/3bw2m4A February 22, 2021 at 05:29PM

Show HN: A no-code billing platform, all under your own domain. https://bit.ly/2NNsSOL

Show HN: A no-code billing platform, all under your own domain. https://bit.ly/3umk5nE February 22, 2021 at 03:47PM

Show HN: Try CLIP, OpenAI's new model, from the browser https://bit.ly/3aFyu6z

Show HN: Try CLIP, OpenAI's new model, from the browser https://bit.ly/3scktmA February 22, 2021 at 05:06PM

Show HN: Kraken Bitcoin Profit Calculator https://bit.ly/3qILSwr

Show HN: Kraken Bitcoin Profit Calculator https://bit.ly/2NPRQN8 February 22, 2021 at 04:35PM

Launch HN: H3X (YC W21) – High power density electric aircraft motors https://bit.ly/3kaoDsB

Launch HN: H3X (YC W21) – High power density electric aircraft motors Hey HN! I’m Jason, one of the co-founders at H3X ( https://bit.ly/2ZHcGB4 ). We are building the lightest electric propulsion systems in the world. Our first product is a 250kW (330HP) integrated motor drive in a 18kg (40lb) package. It combines the electric motor, inverter, and gearbox into a single unit, resulting in an ultra-high-power density solution for electric aircraft (and other mass sensitive applications). In terms of electrification, we believe the aircraft industry is where automotive was ten years ago. There are many companies working on eVTOL and single-seaters, but very few are working on large commercial single-aisle electric aircraft such as a 737. This class of aircraft is absolutely critical to electrify as it accounts for the most passenger-miles [1] and is the biggest slice of the pie in terms of aviation emissions. Beyond the environmental impact, there are huge potential cost savings from both fuel (or lack thereof) and reduced maintenance for airlines. Aircraft are very mass sensitive so there are two main technology challenges that need to be solved to enable this class of electric aviation – (1) High energy density and efficient energy storage (batteries, hydrogen fuel cells, etc.) (2) Light, efficient, and high-power density electric propulsion systems (electric motors, power electronics, gearbox) There are many people working on (1) and great strides are being made [2][3]. We are focused on solving (2). A study done by the DOE determined that for a 737 to complete a five-hour flight, the propulsion system must be >12 kW/kg [4]. Today, best-in-class systems have a power density of 3-4 kW/kg. With our first product, we are targeting 13 kW/kg, making it an attractive solution for near-term Advanced Air Mobility (AAM) applications as well as an enabling technology for the aviation industry to enter the next stage of electrification. There are some cool things we are doing with the electromagnetics, power electronics, and the integration between the systems to get to the 13 kW/kg. There is not a single magic bullet, but rather a combination of multiple technological advances - 3D printed copper stator coils, high frequency SiC power electronics, and a synergistic cooling system to name a few. Our origins in electrification stem back to our college days where we built Formula-style electric racecars (s/o to Wisconsin Racing FSAE!). During year 1 of the program, we got so fed up with our COTS motors and inverters, we decided to go clean slate and build our own from the ground up the following year. Those were super happy fun times. Lots of dead IGBTs and all-nighters in the shop, but in the end, we got everything working and delivered! It was a true test of resilience and taught us how to GSD. Great preparation for starting a company. This led us to grad school and it became apparent during this time that the electric aircraft industry was a sleeping giant ready to be woken. We felt uniquely positioned to capitalize on this opportunity, so after about a year in industry, we left our full-time jobs and went all in. We’ve got a long road ahead - aviation is tough, there’s no denying that. In addition to the engineering challenges, there are also major certification barriers. However, CO2 is a serious problem and right now the major aviation players don’t have a compelling plan to meet the goals laid out in the Paris Agreement. Innovation needs to come from the outside and that’s what we’re doing at H3X. I’d love to hear your guys thoughts and would be happy to answer any questions you have. Sources: [1] https://bit.ly/3ka6tHt [2] https://bit.ly/3kbWtgM... [3] https://bit.ly/2MhK1Qa , https://bit.ly/2ZFLjri [4] ASCEND DE-FOA-0002238 February 22, 2021 at 03:11PM

Show HN: Magic Login – Passwordless login and transactional emails as a service https://bit.ly/2ZBpdGp

Show HN: Magic Login – Passwordless login and transactional emails as a service https://bit.ly/2NurZdZ February 22, 2021 at 02:09PM

Show HN: DeKarmaHN, a Chrome extension to hide karma and more https://bit.ly/3aCwewN

Show HN: DeKarmaHN, a Chrome extension to hide karma and more https://bit.ly/2OVHYlD February 22, 2021 at 04:23AM

Show HN: ProSudoku – Play Sudoku with Apple Pencil on iPad https://bit.ly/3aHbCUo

Show HN: ProSudoku – Play Sudoku with Apple Pencil on iPad https://apple.co/3aG4OpR February 22, 2021 at 02:58AM

Show HN: Building a Binary Counter https://bit.ly/2Nq6z1u

Show HN: Building a Binary Counter https://bit.ly/2NKxxAQ February 22, 2021 at 02:33AM

Show HN: Turn scripts into fine-tuned voices via Wiki markups https://bit.ly/2OOSYkH

Show HN: Turn scripts into fine-tuned voices via Wiki markups https://bit.ly/2NMvpZk February 22, 2021 at 12:59AM

Show HN: A contact form that prunes spam https://bit.ly/3unlhqE

Show HN: A contact form that prunes spam https://bit.ly/2NNswaQ February 21, 2021 at 10:14PM

Show HN: Timelineify – Create Spotify playlists of an artist's full discography https://bit.ly/2ZE74aI

Show HN: Timelineify – Create Spotify playlists of an artist's full discography https://bit.ly/3brYEJ5 February 21, 2021 at 07:43PM

Show HN: Book a table in any restaurant with voice AI and build your own app https://bit.ly/2NKyZTZ

Show HN: Book a table in any restaurant with voice AI and build your own app https://bit.ly/3uiDuG3 February 21, 2021 at 07:24PM